If you’re craving a comforting, nourishing meal that’s bursting with flavor and protein, look no further than this High-Protein Spinach and Artichoke Chicken Casserole Recipe. This dish combines tender shredded chicken with creamy Greek yogurt, tender artichoke hearts, and vibrant spinach, all baked to golden, bubbly perfection. It’s a delightful twist on the classic spinach-artichoke dip we all love, but turned into a wholesome meal that will satisfy your hunger and keep your energy up. Whether you’re meal prepping for the week or hosting a cozy dinner, this casserole is a guaranteed crowd-pleaser that feels indulgent yet wholesome.
Ingredients You’ll Need
Getting started on this High-Protein Spinach and Artichoke Chicken Casserole Recipe is delightfully simple because you only need a handful of straightforward, essential ingredients. Each one plays a crucial role — from creamy textures to fresh flavors and that irresistible cheesy top layer.
- 2 lbs boneless, skinless chicken breasts, cooked and shredded: The protein powerhouse that gives the casserole its hearty base.
- 1 (14 oz) can artichoke hearts, drained and chopped: Adds a tender, slightly tangy bite that brightens the dish.
- 1 (10 oz) package frozen spinach, thawed and drained: Brings vibrant color and earthy flavor plus extra nutrients.
- 1 cup plain Greek yogurt: Contributes creamy richness while boosting the protein content.
- 1 cup cottage cheese: Adds moisture and a mild tang that balances the flavors beautifully.
- 1 cup shredded mozzarella cheese: For that stretchy, melty topping everyone loves.
- ½ cup grated Parmesan cheese: Delivers a sharp, nutty flavor that enhances the cheesy crust.
- 2 cloves garlic, minced: Intensifies the savory profile with aromatic depth.
- 1 teaspoon onion powder: Adds subtle sweetness and complexity without the bulk of fresh onions.
- Salt and pepper to taste: Essential for seasoning and bringing all the flavors together.
How to Make High-Protein Spinach and Artichoke Chicken Casserole Recipe
Step 1: Preheat Your Oven
Set your oven to 375°F (190°C). Preheating ensures that when your casserole goes in, it’ll cook evenly and develop that gorgeous golden crust we all anticipate. This simple first step sets the tone for the perfect bake.
Step 2: Prepare the Filling
In a large mixing bowl, toss together your shredded chicken, chopped artichoke hearts, thawed and drained spinach, Greek yogurt, cottage cheese, minced garlic, onion powder, plus salt and pepper. Take a moment to mix everything until well combined so every bite delivers layers of wholesome, balanced flavor and creamy texture.
Step 3: Assemble the Casserole
Grab a 9×13-inch baking dish and give it a quick grease with oil or non-stick spray to prevent sticking. Spread the prepared chicken mixture evenly in the dish — smooth it out with the back of a spoon to ensure uniform cooking.
Step 4: Add the Cheesy Topping
Sprinkle the shredded mozzarella and grated Parmesan cheese generously over the top of the mixture. These cheeses meld and bubble into a golden, irresistible crust that provides a wonderful contrast to the creamy casserole beneath.
Step 5: Bake Until Bubbling and Golden
Pop your casserole into the oven and bake for 25 to 30 minutes. Watch for the cheese to melt, bubble, and turn a gorgeous golden brown. This signals your casserole is perfectly cooked, packed with smoky, savory goodness, and ready to make your kitchen smell amazing.
Step 6: Cool and Serve
Once baked, allow the casserole to cool for a few minutes to let everything set slightly. If you want, garnish with fresh parsley for a pop of color and fresh herbal note. Serve warm and enjoy the satisfying comfort this High-Protein Spinach and Artichoke Chicken Casserole Recipe offers with each bite.
How to Serve High-Protein Spinach and Artichoke Chicken Casserole Recipe
Garnishes
Fresh parsley or a sprinkle of extra Parmesan on top adds a bright finish and elevates the presentation. A light drizzle of olive oil or freshly cracked black pepper can also add an elegant touch without overpowering those luscious casserole flavors.
Side Dishes
This casserole pairs beautifully with simple sides like a crisp mixed green salad, roasted asparagus, or even a warm whole grain roll to mop up any cheesy goodness. For a lighter spin, some steamed broccoli or a side of quinoa can complement it perfectly while keeping the meal balanced.
Creative Ways to Present
Feeling fancy? Serve individual portions in ramekins for a charming, personalized touch. Alternatively, scoop portions into whole wheat pita pockets or stuff into warm tortillas for a fun, handheld twist that works great for family dinners or lunches on the go.
Make Ahead and Storage
Storing Leftovers
Store any leftovers in an airtight container in the refrigerator for up to 3 to 4 days. The creamy, cheesy flavors meld even further overnight, making the next day’s meal just as delicious—if not better.
Freezing
This casserole freezes wonderfully if you want to prep in advance. Portion it into freezer-safe containers and keep for up to 2 months. Just thaw overnight in the fridge before reheating for a quick and nourishing meal anytime you need one.
Reheating
Reheat individual portions in the microwave or warm the whole casserole in a 350°F (175°C) oven covered with foil to keep moisture, until heated through. Adding a sprinkle of cheese on top before reheating can help refresh that melty, inviting crust.
FAQs
Can I use fresh spinach instead of frozen?
Absolutely! If you prefer fresh spinach, use about 10 ounces, sauté it briefly to wilt, then drain any excess moisture before adding. This will keep your casserole from getting watery and still deliver plenty of green goodness.
Is this recipe suitable for meal prepping?
Yes, it’s perfect for meal prepping! You can make the casserole ahead, refrigerate or freeze it, and then reheat portions throughout the week for a high-protein, convenient meal packed with flavor and nutrition.
Can I substitute the chicken with turkey or another protein?
Sure! Ground turkey, shredded rotisserie chicken, or even cooked lean pork would work well. Just make sure the protein is fully cooked and shredded or chopped to mix evenly with the other ingredients.
How spicy is this casserole?
This casserole is mild and comforting, focusing on creamy, savory flavors without heat. If you like a bit of spice, consider adding a pinch of red pepper flakes or a dash of hot sauce when mixing the filling.
Can I make this recipe dairy-free or vegan?
This recipe relies heavily on dairy for flavor and texture, but with some ingredient swaps—like using dairy-free yogurt, vegan cheese alternatives, and plant-based protein—you could customize it to fit those dietary needs, though it may change the classic taste and texture.
Final Thoughts
If you’re on the hunt for a deliciously wholesome comfort food that doesn’t skimp on protein or flavor, this High-Protein Spinach and Artichoke Chicken Casserole Recipe is your new best friend in the kitchen. It’s cozy, cheesy, and filled with wholesome ingredients that nourish the body and satisfy the soul. I can’t wait for you to try it and make it a regular favorite on your weeknight rotation!
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High-Protein Spinach and Artichoke Chicken Casserole Recipe
- Prep Time: 15 minutes
- Cook Time: 30 minutes
- Total Time: 45 minutes
- Yield: 6 servings
- Category: Main Course
- Method: Baking
- Cuisine: American
- Diet: Low Fat
Description
This High-Protein Spinach and Artichoke Chicken Casserole combines lean chicken breast with nutrient-rich spinach and artichokes in a creamy Greek yogurt and cottage cheese base. Topped with gooey mozzarella and Parmesan cheeses, this hearty casserole is baked to golden perfection, delivering a comforting, protein-packed meal perfect for family dinners or meal prepping.
Ingredients
Main Ingredients
- 2 lbs boneless, skinless chicken breasts, cooked and shredded
- 1 (14 oz) can artichoke hearts, drained and chopped
- 1 (10 oz) package frozen spinach, thawed and drained
- 1 cup plain Greek yogurt
- 1 cup cottage cheese
- 1 cup shredded mozzarella cheese
- ½ cup grated Parmesan cheese
- 2 cloves garlic, minced
- 1 teaspoon onion powder
- Salt and pepper to taste
Instructions
- Preheat Oven: Preheat your oven to 375°F (190°C) to ensure it reaches the right temperature for baking the casserole evenly.
- Prepare the Mixture: In a large mixing bowl, combine the shredded cooked chicken, chopped artichoke hearts, thawed and drained spinach, plain Greek yogurt, cottage cheese, minced garlic, onion powder, and season with salt and pepper. Mix thoroughly until all ingredients are evenly incorporated.
- Assemble the Casserole: Grease a 9×13-inch baking dish to prevent sticking. Spread the prepared chicken and vegetable mixture evenly across the bottom of the dish.
- Add Cheese Topping: Evenly sprinkle the shredded mozzarella cheese and grated Parmesan cheese over the top of the chicken mixture to create a flavorful and golden crust when baked.
- Bake: Place the casserole in the preheated oven and bake for 25 to 30 minutes, or until the casserole is hot, bubbly, and the cheese on top turns golden brown.
- Serve: Remove from oven and let it cool for a few minutes. Optionally garnish with fresh parsley, then serve warm for a delicious high-protein meal.
Notes
- You can use fresh spinach instead of frozen, just be sure to sauté and drain excess moisture before using.
- Cook and shred the chicken breasts ahead of time to save preparation time.
- For extra flavor, add a pinch of crushed red pepper flakes or smoked paprika.
- This casserole can be made ahead of time and refrigerated before baking; just add a few extra minutes to the baking time if baking from cold.
- Leftovers store well in the refrigerator for up to 3 days and can be reheated in the oven or microwave.
